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Lasting health consequences follow premature birth

The health consequences of being born prematurely are broad and enduring, including a higher risk of death throughout childhood and lower reproduction rates as adults, researchers said on Tuesday.

Those are the findings of a study published in the Journal of the American Medical Association that tracked almost 1.2 million people born in Norway from 1967 to 1988.prematurebirth

It is well known that babies delivered before the 37th week of pregnancy, or three weeks before the normal due date, are at higher risk for various medical and developmental problems as infants. Less is known about their long-term health.

The researchers found that while most premature babies went on to have good health and good reproduction, as a group they experienced higher long-term risks than full-term babies.

Preemies, as these premature babies are popularly known, had higher risk of death in childhood, were less likely to reproduce as adults, had slightly lower educational attainment and, among the women, were more likely to have their own babies born prematurely just as they had been.

The overall risk for death among preemies was still low, but was significantly higher than for full-term babies.

The earlier in the pregnancy that a baby was born, the higher the risk of lasting health consequences, said Dr. Geeta Swamy of Duke University Medical Center in Durham, North Carolina, one of the researchers.

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Hormone therapy ups breast cancer recurrence risk: study

LONDON (Reuters) - Hormone replacement therapy, which is known to increase the risk of breast cancer, also appears to make it more likely a tumor will return in women who have had the disease, researchers said on Tuesday.hormone_therapy

Women who had earlier had breast cancer were 14 percent more likely to get it again if they used hormone replacement therapy, or HRT, researchers said in the U.S. Journal of the National Cancer Institute.

"The results ... indicate a substantial risk for a new breast cancer event among breast cancer survivors using hormone-replacement therapy," wrote researcher Lars Holmberg and colleagues at Kings College London.

They followed for four years or longer 442 mostly Scandinavian women who had had breast cancer, half of whom had received HRT.

The women were part of a trial stopped in 2003 after concerns about the increased risk of breast cancer recurring for women on hormone therapy.

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New drug holds promise for parasitic worm disease

U.S. researchers have discovered a promising new drug for schistosomiasis -- a parasitic worm disease that affects more than 200 million people in 70 countries.newdrug

The compound killed worms in the lab, and cured mice infected with the disease, said David Williams of Illinois State University, who reported his findings on Sunday in the journal Nature Medicine.

The only existing drug that works against schistosomiasis, praziquantel, is more than 20 years old.

"There is nothing else you could go to if the parasite evolves resistance," Williams said in a telephone interview. He said about 100 million people will take the drug this year.

"When you treat as many people as are being treated, it is likely drug resistance will evolve," he said.

Schistosomiasis is caused by flatworms that live in snail-invested fresh water. Water becomes contaminated by worm eggs when infected people urinate or defecate in it.

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